منابع مشابه
“Artifactual” arsenate DNA
The recent claim by Wolfe-Simon et al. that the Halomonas bacterial strain GFAJ-1 when grown in arsenate-containing medium with limiting phosphate is able to substitute phosphate with arsenate in biomolecules including nucleic acids and in particular DNA(1) arose much skepticism, primarily due to the very limited chemical stability of arsenate esters (see ref. 2 and references therein). A major...
متن کاملAbsence of detectable arsenate in DNA from arsenate-grown GFAJ-1 cells.
A strain of Halomonas bacteria, GFAJ-1, has been claimed to be able to use arsenate as a nutrient when phosphate is limiting and to specifically incorporate arsenic into its DNA in place of phosphorus. However, we have found that arsenate does not contribute to growth of GFAJ-1 when phosphate is limiting and that DNA purified from cells grown with limiting phosphate and abundant arsenate does n...
متن کاملEvidence for an Artifactual Interpretation
Proponents of unconscious-thought theory assert that letting the unconscious ‘‘mull it over’’ can enhance decisions. In a series of recent studies, researchers demonstrated that participants whose attention was focused on solving a complex problem (i.e., those using conscious thought) made poorer choices, decisions, and judgments than participants whose attention was distracted from the problem...
متن کاملArtifactual Agency In Open Design
We readily use artifacts in theorizing and accounting for epistemic work. Yet the agency characteristics of artifacts and notably their relations to their creators (the subjects) are less understood as agency is more socially privileged than artifactually focused. Rather than understanding the ways artifacts are appropriated as utility objects, we examine the ebb and flow of agency to account f...
متن کاملArtifactual mutations resulting from DNA lesions limit detection levels in ultrasensitive sequencing applications
The need in cancer research or evolutionary biology to detect rare mutations or variants present at very low frequencies (<10-5) poses an increasing demand on lowering the detection limits of available methods. Here we demonstrated that amplifiable DNA lesions introduce important error sources in ultrasensitive technologies such as single molecule PCR (smPCR) applications (e.g. droplet-digital ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Artificial DNA: PNA & XNA
سال: 2012
ISSN: 1949-095X,1949-0968
DOI: 10.4161/adna.19672